Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!
multinodular pattern with unevenly distributed glial cells and an abundant fibrillary matrix. Next - generation sequencing analysis showed balanced genomes without genetic alterations , including single-nucleotide ...
All rights reserved 0950-9232/15 www.nature.com/onc ORIGINAL ARTICLE Next - generation sequencing reveals novel rare fusion events with functional implication in prostate cancer 1 2 3,4 2 2 2 5 6 6 3 I ...
sequencing.Materials and Methods:A hybridization capture-based next - generation sequencing was performed to detected genomic alterations in 50 genes, including androgen receptor, DNA damage response and other clinical ...
. Clinical, radiographic, and pathologic features of tumors were reviewed. Genomic DNA was extracted from formalin-fixed, paraffin-embedded blocks of tumor tissue. Capture-based DNA next - generation sequencing ...
alterations ? FindingsIn a cross-sectional study of next - generation sequencing results collected from 49 participants diagnosed with EHE, more than half of patients with EHE profiled exhibited pathogenic genomic ...
profiled with a next - generation sequencing -based diagnostic assay, two thirds of patients harbored potentially actionable genomic alterations that have the potential to influence and personalize therapy ...
—Comparative Genomic Hybridization (aCGH) showed maternally inherited 16q24.3 deletion, including FANCA gene, and next generation sequencing (NGS) disclosed paternally inherited novel variants in the FANCA gene ...
the patient’s variants, but the studies were not designed specifically to treat pediatric anaplastic astrocytoma.ConclusionsNext- generation sequencing allows genomic characterization of rare diseases ...
and two with intermediate cell carcinomas (ICs) were included. The clinicopathological features were evaluated, and next ‐ generation sequencing was performed in 17 multiregional and longitudinal tumour ...
. ALK positive tumors were subjected to FISH analysis and followed by hybrid capture–based next generation sequencing (NGS). Of the 182 tumors, 8 were ALK positive by IHC. Further analysis using hybrid ...
Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!