Neuroprotective and neurotrophic effects of Lanthionine Ketimine Ester

Neuroprotective and neurotrophic effects of Lanthionine Ketimine Ester •Lanthionine ketimine ethyl ester (LKE) reduces cell death in human SH-SY5Y cells and primary mouse cerebellar granule cells.•LKE reduces glutamate- induced cell death and reactive oxygen species production.•LKE increases neuronal process numbers and lengths.•Reported beneficial actions of LKE in vivo may involve direct actions on neurons as well as suppression of inflammatory responses. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neuroscience Letters Elsevier

Neuroprotective and neurotrophic effects of Lanthionine Ketimine Ester

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier Ltd
ISSN
0304-3940
D.O.I.
10.1016/j.neulet.2017.11.018
Publisher site
See Article on Publisher Site

Abstract

•Lanthionine ketimine ethyl ester (LKE) reduces cell death in human SH-SY5Y cells and primary mouse cerebellar granule cells.•LKE reduces glutamate- induced cell death and reactive oxygen species production.•LKE increases neuronal process numbers and lengths.•Reported beneficial actions of LKE in vivo may involve direct actions on neurons as well as suppression of inflammatory responses.

Journal

Neuroscience LettersElsevier

Published: Jan 18, 2018

References

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