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. This review first provides a descrip- Plastic & Reconstructive Surgery-Global Open tion of the effects and mechanisms of aging in 5 types of tissue: skin, adipose tissue, muscles , bones and tendons, and nervous ...
protein synthesis, the decline of muscle mass, strength, and bone density. Harmful consequences of sarcopenia in old age are loss of muscle strength, inducing itself loss of mobility, neuromuscular ...
increase with age and Kyn is implicated in several age -related disorders including neurodegeneration, osteoporosis, and sarcopenia. Importantly, Kyn increases with progressive disease in HIV patients ...
Frailty is a clinical condition related to changes in metabolism, to sarcopenia, and to decline in muscle mass and strength, bone mineral density, and physical function with aging ...
is an important predictor of health in adult life, while severe mass loss has been associated with the frailty of old age . Studies have shown that skeletal muscle is also an important endocrine organ that secretes ...
; respectively). Muscle measures (ALMI and HGS) contributed more to this association than did bone (SI) (AUROCs 0.77, 0.85 vs 0.71, respectively). In women, only HGS was associated with frailty in adjusted models ...
studies have addressed age related change in bone density; cartilage structure and function; and muscle mass and strength. Environmental influences operating throughout life including nutrition and physical ...
, with a 1% per year decrease in testosterone and a parallel increase in SHBG [9]. The age -related decrease in circulating testosterone associates with decreases in sexual function, bone mass, muscle mass ...
programmes are still lacking. Bone and muscle are neighbours with close ties. We and others have shown that decreases in muscle and bone mass accompany ageing [5-7]. Given the scope of the problem ...
) evaluating the effects of testosterone (T) administration to middle‐ aged and ageing men on body composition, muscle strength, bone density, markers of bone metabolism and serum lipid profile. Data source ...
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