Multi-Omics of Single Cells: Strategies and Applications

Multi-Omics of Single Cells: Strategies and Applications Most genome-wide assays provide averages across large numbers of cells, but recent technological advances promise to overcome this limitation. Pioneering single-cell assays are now available for genome, epigenome, transcriptome, proteome, and metabolome profiling. Here, we describe how these different dimensions can be combined into multi-omics assays that provide comprehensive profiles of the same cell. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Trends in Biotechnology Elsevier

Multi-Omics of Single Cells: Strategies and Applications

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Publisher
Elsevier
Copyright
Copyright © 2016 The Authors
ISSN
0167-7799
D.O.I.
10.1016/j.tibtech.2016.04.004
Publisher site
See Article on Publisher Site

Abstract

Most genome-wide assays provide averages across large numbers of cells, but recent technological advances promise to overcome this limitation. Pioneering single-cell assays are now available for genome, epigenome, transcriptome, proteome, and metabolome profiling. Here, we describe how these different dimensions can be combined into multi-omics assays that provide comprehensive profiles of the same cell.

Journal

Trends in BiotechnologyElsevier

Published: Aug 1, 2016

References

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