mRNA expression and metabolic regulation of npy and agrp1/2 in the zebrafish brain

mRNA expression and metabolic regulation of npy and agrp1/2 in the zebrafish brain •We analyzed npy, agrp1, and agrp2 mRNA distribution in larval/adult zebrafish brains.•NPY and AGRP1 neurons function as GABAergic inhibitory neurons in larval zebrafish.•Npy and agrp1/2 are expressed in distinct neurons in the hypothalamus.•Metabolic state regulated NPY neurons in the lateral hypothalamus of adult zebrafish.•Metabolic state regulated AgRP1 neurons in the adult zebrafish ventral hypothalamus. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neuroscience Letters Elsevier

mRNA expression and metabolic regulation of npy and agrp1/2 in the zebrafish brain

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Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier B.V.
ISSN
0304-3940
D.O.I.
10.1016/j.neulet.2018.01.017
Publisher site
See Article on Publisher Site

Abstract

•We analyzed npy, agrp1, and agrp2 mRNA distribution in larval/adult zebrafish brains.•NPY and AGRP1 neurons function as GABAergic inhibitory neurons in larval zebrafish.•Npy and agrp1/2 are expressed in distinct neurons in the hypothalamus.•Metabolic state regulated NPY neurons in the lateral hypothalamus of adult zebrafish.•Metabolic state regulated AgRP1 neurons in the adult zebrafish ventral hypothalamus.

Journal

Neuroscience LettersElsevier

Published: Mar 6, 2018

References

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