Morphine antinociception on thermal sensitivity and place conditioning in male and female rats treated with intraplantar complete freund’s adjuvant

Morphine antinociception on thermal sensitivity and place conditioning in male and female rats... •Morphine antinociception is sexually dimorphic one day after CFA-induced persistent nociception.•Sex differences in morphine antinociception were resolved seven days after CFA treatment.•Morphine conditioned place preference in CFA treated rats was enhanced over time.•Sexually dimorphic morphine antinociception is impacted by the chronicity of pain. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Behavioural Brain Research Elsevier

Morphine antinociception on thermal sensitivity and place conditioning in male and female rats treated with intraplantar complete freund’s adjuvant

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Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier B.V.
ISSN
0166-4328
D.O.I.
10.1016/j.bbr.2018.01.031
Publisher site
See Article on Publisher Site

Abstract

•Morphine antinociception is sexually dimorphic one day after CFA-induced persistent nociception.•Sex differences in morphine antinociception were resolved seven days after CFA treatment.•Morphine conditioned place preference in CFA treated rats was enhanced over time.•Sexually dimorphic morphine antinociception is impacted by the chronicity of pain.

Journal

Behavioural Brain ResearchElsevier

Published: May 2, 2018

References

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