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for the development and regulation of inhalation aerosol products. dry powder inhaler, electrostatic charge, meter dose inhaler, nebuliser, pharmaceutical aerosol, spacer Introduction Active pharmaceutical ingredients ...
Abstract This review seeks to offer a broad perspective that encompasses an understanding of the drug product attributes affected by active pharmaceutical ingredient (API) physical properties ...
. Figure 1 Open in new tabDownload slide Hot-melt extrusion (HME) equipment and process parameters traditionally monitored during pharmaceutical HME. (1. Feeding system; 2. Feeding hopper; 3. Temperature ...
Abstract Objectives The main aim of this review was to develop a critical discussion of the key role ultrasound (US) can play on the production of active pharmaceutical ingredients (APIs ...
with nicotinamide Phase transformation during dissolution 2013[78] Carbamazepine Cocrystal of drug with nicotinamide Surfactant effects on dissolution behaviour 2013[79] Indomethacin Nanocrystal powder Surface ...
Nordisk A/S, Bagsværd, Denmark) is a breath- activated inhalation system that also allows for patient monitoring in order to ensure compliance to an adequate inhalation technique at optimal breathing ...
/incomplete delivery of the active pharmaceutical ingredient (API) from its formulation in an appropriate time frame, resulting in elimination from the gastrointestinal tract before absorption (dissolution ...
neuronal cell loss occurs (e.g. CA1 and hilus). Conclusions: Our data indicate that within the immune response the complement activation represents a prominent process during epileptogenesis. The persistence ...
, tested zebrafish are housed together, and monitored for 24 hours for morphological (e.g. adhesions, bruising or abrasion to the skin) and abnormal swim defects. If any zebrafish exhibit these effects ...
-in-water dispersions are generated.[5] During these phase changes, a compound that is solubilized in the self-emulsifying system will migrate into oil-rich or water-rich domains, depending on its ...
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