Micro-AbstractPatients with advanced colorectal were enrolled in a molecular profiling program. Of 245 patients, at least one mutation was found in 64.5% patients, with TP53, RAS, APC and PIK3CA being the most common mutations. Right colon cancers harbor more molecular aberrations than left colon or rectal cancers. This difference may contribute to differential outcomes to anti-epidermal growth factor receptor therapy.
Clinical Colorectal Cancer – Elsevier
Published: Mar 1, 2018
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