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modulate neutrophil recruitment by acting on NK-1 receptors in rat airways in vivo. Human bronchial epithelial cells in vitro respond to stimulation with IL-17 by increasing the production and release ...
cells to IL-1β mimicked the changes observed in patients with UC. An IL-1β–induced reduction in contraction and release of intracellular Ca2+in response to NKA was partially restored by the hydrogen ...
of cytokine release and modulation of susceptibility to infection by cytokine exposure. J Clin Invest.1995;96:549-557.Google Scholar 15. Matsukura S, Kokubu F, Noda H, Tokunaga H, Adachi M. Expression of IL-6 ...
largeDownload slide The circle of neuroimmune communication. Cytokines and secondary production of prostaglandins sensitize nociceptive sensory neurons. This results in an increased release of the neuropeptides ...
edema. Conclusions/Significance In conclusion, MLV induces paw edema in rats by mechanisms involving activation of mast cells and substance P- releasing sensory C-fibers. Tachykinins NKA and NKB, histamine ...
), a neuropeptide of the tachykinin family produced by neurons, endothelial cells, and lymphocytes, is observed [43]. The secretion of SP is tightly associated with the expression of inflammatory type 1 cytokines ...
of proinflammatory cytokines , and production of new immune cells. Substance P also stimulates the release of histamine from mast cells, which further amplifies the inflammatory response. The major site of peripheral ...
or modulate aspects of intestinal inflammation through secretion of neuropeptides that serve as a link between the ENS and CNS. Neuropeptides are defined as any peptide released from the nervous system ...
of activating mast cells. After activation, mast cells release histamine, leukotrienes, prostanoids, proteases, many growth factors, and cytokines , which in turn can excite and stimulate the surrounding ...
. In addition to these exogenous trigger factors, endogenous stimuli such as like protons (pH changes), hormones, cytokines , proteinases, kinins, and probably other undefined mediators released by various cells ...
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