Model lipid bilayers mimic non-specific interactions of gold nanoparticles with macrophage plasma membranes

Model lipid bilayers mimic non-specific interactions of gold nanoparticles with macrophage plasma... Journal of Colloid and Interface Science 516 (2018) 284–294 Contents lists available at ScienceDirect Journal of Colloid and Interface Science journal homepage: www.elsevier.com/locate/jcis Regular Article Model lipid bilayers mimic non-specific interactions of gold nanoparticles with macrophage plasma membranes a,⇑ a b c b a Costanza Montis , Viola Generini , Giulia Boccalini , Paolo Bergese , Daniele Bani , Debora Berti Department of Chemistry and CSGI, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy Department of Experimental and Clinical Medicine, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy Department of Molecular and Translational Medicine, CSGI and INSTM, University of Brescia, 25123 Brescia, Brescia, Italy graphical a bstract ar ti c l e i nf o ab stra ct Article history: Understanding the interaction between nanomaterials and biological interfaces is a key unmet goal that Received 6 December 2017 still hampers clinical translation of nanomedicine. Here we investigate and compare non-specific inter- Revised 17 January 2018 action of gold nanoparticles (AuNPs) with synthetic lipid and wild type macrophage membranes. A com- Accepted 18 January 2018 prehensive data set was generated by systematically varying the structural and physicochemical Available online 6 February 2018 properties of the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Colloid and Interface Science Elsevier

Model lipid bilayers mimic non-specific interactions of gold nanoparticles with macrophage plasma membranes

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Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier Inc.
ISSN
0021-9797
eISSN
1095-7103
D.O.I.
10.1016/j.jcis.2018.01.064
Publisher site
See Article on Publisher Site

Abstract

Journal of Colloid and Interface Science 516 (2018) 284–294 Contents lists available at ScienceDirect Journal of Colloid and Interface Science journal homepage: www.elsevier.com/locate/jcis Regular Article Model lipid bilayers mimic non-specific interactions of gold nanoparticles with macrophage plasma membranes a,⇑ a b c b a Costanza Montis , Viola Generini , Giulia Boccalini , Paolo Bergese , Daniele Bani , Debora Berti Department of Chemistry and CSGI, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy Department of Experimental and Clinical Medicine, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy Department of Molecular and Translational Medicine, CSGI and INSTM, University of Brescia, 25123 Brescia, Brescia, Italy graphical a bstract ar ti c l e i nf o ab stra ct Article history: Understanding the interaction between nanomaterials and biological interfaces is a key unmet goal that Received 6 December 2017 still hampers clinical translation of nanomedicine. Here we investigate and compare non-specific inter- Revised 17 January 2018 action of gold nanoparticles (AuNPs) with synthetic lipid and wild type macrophage membranes. A com- Accepted 18 January 2018 prehensive data set was generated by systematically varying the structural and physicochemical Available online 6 February 2018 properties of the

Journal

Journal of Colloid and Interface ScienceElsevier

Published: Apr 15, 2018

References

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