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simulations are performed to model the interaction of an amphiphilic MUS:OT NP with a dioleoylphosphatidylcholine (DOPC) bilayer . Following previous work [16, 29, 36, 49, 50], the NP gold core is modeled ...
physiological and pathological processes. Supported lipid bilayers (SLBs) of increasing complexity are excellent membrane model systems to investigate the effects of lipid composition and phase on the membrane ...
] and modeled the transmembrane domains (TMDs) on the structure based on their amino acid sequence. The resulting model was placed in a multi-component bilayer , whose lipid composition mimics that of the ER (S1A ...
, hydrophilicity of membranes, and affecting the mechanical properties (e.g., bending modulus) of the bilayer [1–3]. As the model of biomembranes (i.e., plasma membrane), artificial membranes comprising of lipids ...
, showing strong non - specific interaction with the blank channel, virtually no dissociation of antibody from the immobilized GD3 was observed during the dissociation phase (apparent kd = 8.8 × 10−5 s−1, data ...
of the used models were described previously [59]. Results Establishing robust surface conjugation In order to study FG Nup behavior and its interaction with TFs and non - specific proteins, we established ...
was inserted in the bilayer and AFM to estimate the height of the protrusions in the lipid bilayer . Our atomistic model of Bot1 can be used to map and predict effects of changes on structure and function ...
fluid lipid bilayers to explore the formation and movement of these dynamic protein domains.33,66 Fluid lipid bilayer substrates are coated with phospholipid molecules which mimic the natural bilayer ...
the structure of the interior of the NPC. According to the virtual gate model [4], [18], the tethered, unstructured FG-repeat proteins form an entropic barrier that repels non - specific cargo, preventing it from ...
of the charge distribution on LHCII trimers exposed on the stromal surface, it was suggested that non - specific interaction of positively charged N-terminal peptides on one membrane with a negatively charged ...
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