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- 3p directly targets E2F1 and induces growth arrest in human gastric cancer . Biochem. Biophys. Res. Commun ., 398 , 1 – 6 . Google Scholar CrossRef Search ADS PubMed 18. Cao , Y. , et al. ( 2015 ) Hsa ...
cells by binding TLR8, inducing a pro-metastatic inflammatory response, which might contribute towards tumour growth and tumour metastasis.[33] Thus, in many ways, any alteration to miRNA biogenesis ...
0.0001 rno-miR-125b-5p −1.80 0.03 0.0001 −1.67 0.03 0.0001 Open in new tab Functional analysis of the riddelliine- induced DEMs miRNAs function through binding to the 3′-untranslated region of their target ...
-590- 3p Homer1, Hopx, Clic5 Intracardiac injection of mimic or systemic administration of targeted exosomes induce regeneration in rodents 64,75 miR-1825 NDUFA10 and other genes involved in mitochondrial ...
) and vascular endothelial growth factor in renal cell carcinoma or by fibroblast growth factor receptor 3 and p53 in bladder cancer. Many miRNAs are predicted to target important signaling pathways in urological ...
study, Lai et al. [15] validated that hsa-miR-205-5p and hsa-miR-342- 3p achieve an enhanced repressive effect on E2F1 expression in a cooperative manner in an aggressive human non-small cell lung ...
expression by directly binding to PRC1 and PRC2. ANRIL, which is induced by E2F1 , increases CDK6 activity by repressing its inhibitors (miR-99a/miR-449a) (B). lncRNA-ATB inhibits miR-200 and thereby promotes ...
-Kikkatalo et al., 2014). Since many of the secreted molecules are known targets for autoimmune reactions, the human endometrium has been proposed as a highly immune-privileged tissue that reduces ...
with metastatic PCa. Commonly administered therapeutics include Enzalutamide, Bicalutamide, and Abiraterone [2]. These drugs inhibit the androgen signaling axis, a growth and differentiation- inducing pathway ...
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