Probiotics are used in food products, dietary supplements and pharmaceutical products because they may provide health-promoting effects in humans. To be efficacious, probiotics need to be viable at sufficient abundance within the large intestine. However, many commercial products containing probiotics suffer from a substantial loss of bacterial viability during shelf storage and during gastrointestinal transit. In this study, a probiotic (Lactobacillus salivarious Li01) was incorporated into either alginate or alginate-gelatin microgels. The morphology of the microgels was characterized by scanning electron microscopy, which indicated that they had a spherical shape and that almost all of the bacterial cells were encapsulated inside them. Probiotic viability was determined under aerobic conditions, heat treatment, and simulated gastrointestinal conditions. Encapsulation significantly enhanced the viability of the probiotic during aerobic storage. The microgels maintained their structures under simulated gastric conditions, but either eroded or swelled under simulated small intestine conditions. The alginate-gelatin microgels were the most effective at protecting the bacteria under simulated gastrointestinal conditions when compared to the alginate microgels and non-encapsulated bacteria. In conclusion, alginate-gelatin microgels have great potential for the protection and delivery of probiotics in food, supplement, and pharmaceutical products.
Food Hydrocolloids – Elsevier
Published: Nov 1, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera