Methyl parathion inhibits the nuclear maturation, decreases the cytoplasmic quality in oocytes and alters the developmental potential of embryos of Swiss albino mice

Methyl parathion inhibits the nuclear maturation, decreases the cytoplasmic quality in oocytes... Introduction</h5> Organophosphorous group of pesticides are commonly used in the agricultural system due to their rapid action on the pests or insects. Increased exposure of these pesticides to public is mainly thought to be due to their illegal indoor exposure ( Ruckart et al., 2004 ). Methyl parathion ( O , O -dimethyl- O -4- p -nitrophenyl phosphorothioate, MP), commonly known as “cotton poison” ( Ruckart et al., 2004 ), is one of the widely used organophosphorous pesticide classified by the U.S. Environmental Protection Agency as Class I restricted use pesticide ( Jaga and Dharmani, 2006 ). It has a wide application as insecticide and herbicide in the agricultural field ( Garcia et al., 2003 ). Despite its rapid degradation in soil, it can be transported to the surrounding areas through natural agents such as rain, fog and wind thus increasing the risk of exposure to human ( Sakellarides et al., 2002 ).</P>Human beings are exposed to methyl parathion through the respiratory tract, skin and gastrointestinal tract ( Rehner et al., 2000; Zhu et al., 2001 ). Studies from various parts of the world have shown that vegetables and fruits collected from the market are contaminated with organophosphorous http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Toxicology and Applied Pharmacology Elsevier

Methyl parathion inhibits the nuclear maturation, decreases the cytoplasmic quality in oocytes and alters the developmental potential of embryos of Swiss albino mice

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Publisher
Elsevier
Copyright
Copyright © 2014 Elsevier Inc.
ISSN
0041-008x
D.O.I.
10.1016/j.taap.2014.07.004
Publisher site
See Article on Publisher Site

Abstract

Introduction</h5> Organophosphorous group of pesticides are commonly used in the agricultural system due to their rapid action on the pests or insects. Increased exposure of these pesticides to public is mainly thought to be due to their illegal indoor exposure ( Ruckart et al., 2004 ). Methyl parathion ( O , O -dimethyl- O -4- p -nitrophenyl phosphorothioate, MP), commonly known as “cotton poison” ( Ruckart et al., 2004 ), is one of the widely used organophosphorous pesticide classified by the U.S. Environmental Protection Agency as Class I restricted use pesticide ( Jaga and Dharmani, 2006 ). It has a wide application as insecticide and herbicide in the agricultural field ( Garcia et al., 2003 ). Despite its rapid degradation in soil, it can be transported to the surrounding areas through natural agents such as rain, fog and wind thus increasing the risk of exposure to human ( Sakellarides et al., 2002 ).</P>Human beings are exposed to methyl parathion through the respiratory tract, skin and gastrointestinal tract ( Rehner et al., 2000; Zhu et al., 2001 ). Studies from various parts of the world have shown that vegetables and fruits collected from the market are contaminated with organophosphorous

Journal

Toxicology and Applied PharmacologyElsevier

Published: Sep 15, 2014

References

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