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of the osteoblast and osteoclast lineages. Mitogenic factors playing a role in fracture repair may act by regulating HGF / SF expression or activity in bone-forming cells. We investigated the effect of fibroblast ...
at concentrations of more than 0.1 or 1 IU/ml. IFN‐α and IFN‐β were as effective as IFN‐γ in RPMI‐8226 cells, but less than IFN‐γ in KG‐1 cells. HGF / SF gene expression in KG‐1 cells was also up‐ regulated by IFN‐γ ...
), all of which increase the expression of HGF / SF in human skin fibroblasts or MRC-5 cells. Transforming growth factor-β and some glucocorticoids down- regulate HGF / SF production in leukaemia cell cultures ...
was confined to a subset of tumor cells, and signals were less intense than in glioblasto mas. In addition, we detected SF / HGF mRNA in cortical neurons. SF / HGF expression was not up regulated around necroses ...
gingival fibroblasts ( HGF ). RT-PCR analysis revealed that CXCL12 and CXCR4 mRNA were expressed in both normal gingival tissues and periodontal diseased tissues. Immunohistochemistry disclosed that CXCL12 ...
savolitinib in an arthritis model mice. Methods HGF /c-Met expression in serum, SF and synovial tissues (STs) obtained from RA patients and controls, as well as RA fibroblast -like synoviocytes (FLSs ...
), and to the mesothelial layer beneath the chorionic girdle (Fig. 4, c and d). In summary, therefore, the HGF - SF gene was expressed in mesoderm, and its receptor, c-met, was expressed in trophoblast, mesoderm, and endoderm ...
extracellular matrix degradation, tubule formation, and angiogenesis in vivo. SF / HGF induces brain tumor angiogenesis directly through only partly known mechanisms and indirectly by regulating other angiogenic ...
to elucidate the mechanism . We show that HGFs express CRLR and RAMP2 constitutively. Choksi and colleagues reported that Rat-2 fibroblast expressed CRLR and RAMP2 [30]. They found no RAMP3 expression in Rat-2 ...
, inflammation and apoptosis. In this study, we investigated TWEAK expression in periodontally diseased tissues and the effect of TWEAK on human gingival fibroblasts ( HGF ). Reverse transcription–polymerase chain ...
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