</P>Professor Marija Alačević, a pioneer in the application of genetic approaches in biotechnology, and a driving force in bringing genetic toxicology research and testing to the former Yugoslavia, died in Zagreb, Croatia on February 25, 2015. Her successful and numerous collaborations with scientists from the pharmaceutical industry on understanding genetic recombination in Streptomyces formed the basis for the “Zagreb School of Streptomyces Genetics,” and greatly improved the production of tetracycline antibiotics.</P>Marija Alačević was born in Makarska, a picturesque town on the Adriatic coast of Croatia. Technically oriented, she studied electrical engineering for three years before discovering that the real challenge for her was in the complexity of living matter. In 1954 she received her B.S. in Biology at Zagreb University, and shortly thereafter joined the Faculty of Technology, the Department of Biotechnology at Zagreb University. As a scientist with a technical background and an evolving interest in genetics, she was in an ideal position to join the rapidly developing field of biotechnology led by Professor Vera Johanides, a prominent figure in industrial microbiology. Through collaborations with the geneticist Giuseppe Sermonti at the Istituto Superiore di Sanita in Rome, Marija mastered Streptomyces genetics and in 1965 completed her PhD
Mutation Research - Genetic Toxicology and Environmental Mutagenesis – Elsevier
Published: Jun 1, 2015
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