LPS Transport: Flipping Out over MsbA

LPS Transport: Flipping Out over MsbA Lipopolysaccharide synthesis and transport pathways are attractive targets for the development of new antimicrobial therapeutics. The ABC (ATP Binding Cassette) transporter MsbA has been recently described as employing a ‘trap and flip’ mechanism of lipopolysaccharide transport. This represents a novel mechanism amongst known lipid ABC transporters. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Biology Elsevier

LPS Transport: Flipping Out over MsbA

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Publisher
Cell Press
Copyright
Copyright © 2017 Elsevier Ltd
ISSN
0960-9822
D.O.I.
10.1016/j.cub.2017.10.067
Publisher site
See Article on Publisher Site

Abstract

Lipopolysaccharide synthesis and transport pathways are attractive targets for the development of new antimicrobial therapeutics. The ABC (ATP Binding Cassette) transporter MsbA has been recently described as employing a ‘trap and flip’ mechanism of lipopolysaccharide transport. This represents a novel mechanism amongst known lipid ABC transporters.

Journal

Current BiologyElsevier

Published: Jan 8, 2018

References

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