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, Bortolucci A. Low frequency of Roberts K, Harrison CJ. ETV6/ AML1 fusion by FISH in adult acute the TEL / AML1 fusion gene in acute lymphoblastic leukaemia in lymphoblastic leukemia . Leukemia 2002; 16: 669–674 ...
-polymerase chain reaction (RT-PCR), the TEL - AML1 chimeric transcript has been observed in 22–27% of pediatric patients with acute lymphoblastic leukemia (ALL), in particular in the early B-lineage ALL subtype ...
with pediatric acute lymphoblastic leukemia (ALL) and is exclusively associated with precursor B cell leukemia . This chimeric gene arises predominantly during fetal hemopoiesis and TEL - AML1 -expressing fetal clones ...
on childhood acute lymphoblastic leukemia (ALL), which accounts for 80% of pediatric leukemia . Because healthy children have higher frequencies of HGs than adults , and there are significant differences between ...
– 612 . Google Scholar Crossref Search ADS PubMed WorldCat 4 SP Romana , H Poirel, M Leconiat et al. High frequency of t(12;21) in childhood B-lineage acute lymphoblastic leukemia . Blood 1995 ; 86 : 4263 ...
will be informed of a new chemotherapy agent that is indicated for the treatment of adults with Philadelphia chromosome-negative acute lymphoblastic leukemia , whose disease has relapsed two or more times or whose ...
of transient myeloproliferative disease and acute megakaryoblastic leukemia in children with DS. Determine the clinical and biologic features of acute lymphoblastic leukemia in children with DS and outline ...
pediatric and adult precursor B lymphoblastic leukemias [24–29]. In pediatric leukemias , low rate of cell division and high expression of INK4A may be associated with in vitro drug resistance or poor clinical ...
onset acute leukemia [32, 33]. The most common mutation in pediatric ALL is TEL - AML1 that also arises in utero [34, 35]. However, studies show that this mutation is not enough to lead to the full ...
) and acute lymphoblastic leukemia (ALL) [29,30], and the BCL2-IGH and IGH-cMyc fusion events, associated with follicular non-Hodgkin lymphoma [31,32]. Interestingly, some translocations appear to occur very ...
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