THE JOURNAL OF PEDIATRICS � www.jpeds.com MEDICAL PROGRESS Fiona M. Baumer, MD, Aaron L. Cardon, MD, MSc, and Brenda E. Porter, MD, PhD pilepsy is one of the most common and severe neu- assessment of language extremely difﬁcult; this review will there- rologic diseases in children, affecting 0.9%-2% of the fore focus on studies of children with normal or near-normal 1,2 E pediatric population. Children and adolescents with intelligence. This paper will ﬁrst review studies characteriz- epilepsy and their parents indicate that quality of life is driven ing language deﬁcits in pediatric epilepsy from the most severe as much or more by cognitive comorbidities as by seizure forms with total loss of language to the more common forms 3-5 control. Surveys of these families found that cognitive prob- of language impairment found in the inappropriately termed lems were second only to medication side effects in terms of “benign” epilepsies of childhood. Next, we will describe what decreasing quality of life. The new International League Against is known about the structural and electrophysiologic changes Epilepsy classiﬁcation considers the cognitive comorbidities seen associated with language dysfunction, reviewing the in epilepsy to be part of the condition. Of the cognitive prob- neuroimaging,
The Journal of Pediatrics – Elsevier
Published: Mar 1, 2018
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