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JE , Merriam A, Awadallah A et al. A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse . J Bone Miner Res 1999 ; 14 : 700 – 709 . Google Scholar Crossref Search ADS ...
and are multipotential , while single cells from the adult dentate gyrus (DG) produce small, unipotent, and nonself-renewing colonies. We find that multipotential and long-term self-renewing colonies can be isolated only ...
of the multilineage mesenchymal differentiation potential of cells derived from collagenase-treated human trabecular bone fragments has prompted further interest in view of the potential application of mesenchymal ...
. Populations derived from a single cell were then used for multipotential experiments, differentiating along all three (adipogenic, chondrogenic, and osteogenic) lineages. These studies were repeated ...
—to specifically identify the ALDHbr population (Fig. 1A). Figure 1. Open in new tabDownload slide Identification , isolation , and differentiation of SSCloALDHbr cells from murine brain. (A, B): Representative flow ...
]. Furthermore, some reports have indicated that cells differentiated from NCCs also have multipotential cell fate. Pigmented cells isolated from the skin of quail embryos were able to generate glial cells ...
. They show a multipotentiality for differentiation not only into osteoblasts and adipocytes but also into vascular endothelial cells, indicating that these cells are mMSCs in nature. Furthermore, the FMS/ PA6 ...
the adherent cells. We have previously reported that cells isolated from human BM in this way have the capability to give rise to progeny of osteocytes, indicating their multipotentiality [11]. In this study, we ...
and Nanog in freshly isolated mesenchymal stem cells (MSC), and demonstrate that their expression is lost when the cells are placed in culture [8]. Knockdown of Oct4 and Nanog led to decreased differentiation ...
and in regenerative therapies.5 In a Related Article from STEM CELLS, Nakagomi et al described how brain vascular pericytes acquire multipotential differentiation capabilities and differentiate into major components ...
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