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to an independent way of life [5]. Although cardiac arrest is the initiating event, the degree of disability and mortality in patients undergoing CPR is primarily determined by the extend of injury to the brain [ 6 ...
neuroprotection in a gerbil model of ischemic stroke. A 10-min period of global cerebral ischemia , induced by occluding both common carotid arteries, caused impairment in spatial learning and memory ...
cerebral ventricular application of EPO during cerebral hypoxia- ischemia illustrate a reduction in ischemia - induced learning disability , increased neuronal survival, and the development of ischemic tolerance ...
1. IL-4 improves white matter integrity upon demyelination. Transient focal ischemia was induced in WT and IL-4 KO mice by 60-min MCAO. (A-D) Flow cytometric analysis of IL-4R in brain cells of WT ...
, left) and TNF-α (F[1,8] = 16.732, P = .003; Figure 2B, left). Figure 2. Open in new tabDownload slide Nicotine prevents lipopolysaccharide (LPS)- induced increase of interleukin -1 beta (IL-1β) and tumor ...
inflammation and mediates an intracellular negative feedback loop in microglial cells that leads to suppression of inducible nitric oxide synthetase induction. Thus, endocannabinoids prevent dangerous ...
. The sixth group (stroke & SO2) was subjected to cerebral ischemia for 180 min by MCAO and then exposed to SO2 (7.00 ± 0.78 mg/m3) for 6 h/day for 7 days. The seventh group (only MCAO) and the eighth group ...
Enhanced endogenous neurogenesis Parkinson’s [34] Bone marrow 6 -OHDA mice NTF secretion Enhanced dopaminergic neurons survival Enhanced endogenous neurogenesis Parkinson’s [36] Bone marrow MPTP- induced mice ...
alpha and interleukins 6 , 8 and 11 [31, 32]. It is thought that angiogenic cytokines secreted from MSCs induce increases in proliferation and mobilization of endothelial cells. However ...
.62,63 Supplementation with n-3 PUFA also reduced oxidative damage and prevented learning disability (based on the Morris water maze) in rats with traumatic brain injury.64 Recently, considerable research ...
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