Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!
bioassays currently used for ciguatoxin analysis; however, similarly to the other chemical-based or bioassays that have been developed, it faces challenges due to limited standards and interlaboratory ...
, screened in different in vitro assays, was compared with two human U2-OS cell line–based CALUX® (Chemically Activated LUciferase eXpression) reporter gene assays for androgens (AR CALUX) and estrogens (ERα ...
a QPCR-based signature using these samples. When combined with a standardized test procedure and prospective interlaboratory validation, the accuracy and potential utility in preclinical applications can ...
with the in vivo uterotrophic assay, but is expected to suffer from the same drawbacks as the uterotrophic assay, as the selected in vitro bioassays only measure effects directly mediated by ERα, and are not able ...
. In vitro assays for new drug screening : Comparison of a thymidine incorporation assay with the human tumor colony-forming assay. Int. J. Cell Cloning 5(5):421–431. Efforts were made to determine ...
and culture media. J. In Vitro Fert. Embryo Transf. 5(2):67-75. A rapid bioassay procedure is described for quality-control testing of water and apparatus used in the preparation of media for gamete and embryo ...
in vitro test for carcinogens. Hanauske, U., A. R. Hanauske, G. M. Clark, D. Tsen, J. Buchok and D. D. Von Hoff. 1989. A new in vitro screening system for anticancer drugs for the treatment of non-small-cell ...
believe it is prudent to employ tests capable of detecting the broadest range of genotoxic mechanisms. In Vitro Assays Lack Value Because of a Lack of Correlation with Rodent Bioassay Results This issue ...
to −3. We did not use Tox21 high-throughput screening (HTS) data as a primary source for comparison due to concerns of inter- and intrasample variability, assay sensitivity and purity of the samples (less ...
Abstract An in vitro micronucleus assay using the permanent fish cell line RTG-2 (rainbow trout gonads) was developed to test industrial waste waters for their genotoxic potential. Comparison of flow ...
Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!