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present a landmark transcriptomic dataset that provides a comprehensive view of spatiotemporal organization of processes in the post- ischemic brain and documents the conservation of glial response in CNS ...
The immune response after stroke is known to play a major role in ischemic brain pathobiology. The inflammatory signals released by immune mediators activated by brain injury sets off a complex ...
the natural responses of glial cells after injury to reduce the size of lesions and increase axon regrowth into lesion core environments. These results support the use of pTreGuo hydrogels as part of neural ...
in the aged or after stroke. We found that after focal striatal ischemic infarction in adult rats, SC1 increased in astrocytes surrounding the infarct and in the glial scar, but in aged rats, SC1 was lower ...
Intracerebral hemorrhage (ICH) usually affects older humans but almost no experimental studies have assessed aged animals. We address how aging alters inflammation , neuron death and lesion resolution ...
Schroeter M Inflammation and glial responses in ischemic brain lesions Prog. Neurobiol. 1998 56 149 171 Google Scholar CrossRef Search ADS PubMed Stoltenburg-Didinger G Pünder I Peters B Marcinkowski M ...
Background: Cerebral ischemia is associated with the activation of glial cells, infiltration of leukocytes and an increase in inflammatory mediators in the ischemic brain and systemic circulation ...
cells acting as early responders (Silver and Curley ), whereas additional late‐phase responses include reactive astrocytosis and the resulting glial scar formation in the boundary zone of the ischemic ...
and numerous foreign body type multinucleated giant cells. Vessels with calcified walls were also identified. The surrounding capsule contained reactive glial cells and vessels with perivascular inflammation ...
phase of brain ischaemia, although immune response by T lymphocytes (innate or acquired immunity) is also implicated in inflammation at the subacute phase, which sustains ischaemic brain damage ...
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