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2005 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in the U.S.A. Identification of Mammalian Proteins Cross - linked to DNA by Ionizing Radiation Received for publication ...
), double-strand breaks (DSBs), oxidized base lesions, and DNA - protein cross links . Among them, DSB is the most deleterious lesion since lack or mis-repair of DSBs can result in chromosomal instability ...
radiation - or apurinic), DNA ± DNA and DNA ± protein cross - links induced clustered DNA damage containing base along with a plethora of base modi®cations (1±3). Many lesions was investigated in plasmid DNA under ...
The Fanconi anemia D2 protein is vital for cellular resistance to DNA cross - linking . Now, FANCD2 is shown to also be involved in a second, independent function, the arrest of DNA synthesis after ...
The death ligand TRAIL synergizes with DNA -damaging therapies such as chemotherapeutic drugs or ionizing irradiation. Here, we show that the synergism of TRAIL and 5-fluorouracil (5-FU) and cross ...
and DSBs, base damage, DNA – protein cross - links , as well as radiation -induced oxidative damage. The involvement of DNA strand breaks in AR is emphasized from the observation that adaptation can be abolished ...
, time lapse video microscopy. Introduction Studies of ionizing and ultraviolet (UVC, 254 nm) radiation -induced DNA damage and repair in human cells have largely focused on the response of primary ...
Placeholder Text WorldCat 8. Nakano T , Mitsusada Y, Salem AM et al. Induction of DNA - protein cross - links by ionizing radiation and their elimination from the genome . Mutat Res 2015 ; 771 : 45 – 50 . Google ...
), double‐strand breaks (DSB), AP sites (either apyrimidinic or apurinic), DNA – DNA and DNA – protein cross ‐ links along with a plethora of base modifications (1–3). Many endogenous DNA lesions, formed ...
and extrapolation to man. Fundam. Appl. Toxicol. , 17, 409–428. Google Scholar Casanova,M., Morgan,K.T., Gross,E.A., Moss,O.R. and Heck,H.d'A. ( 1994) DNA – protein cross - links and cell replication at specific sites ...
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