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A single inner centromere protein ( INCENP ) found throughout eukaryotes modulates Aurora B kinase activity and chromosomal passenger complex (CPC) localization, which is essential for timely mitotic ...
during G2/M-phases. A conserved mitotic kinase , Aurora B, is activated during M-phase by association with INCENP , forming the chromosome passenger complex with Borealin and Survivin. We show that Cdc7 ...
, which, together with Aurora B, form the chromosome passenger complex (CPC). However, besides Aurora homologs, only a candidate gene with restricted homology to INCENP has been described in Arabidopsis ...
is the only Aurora kinase essential for MI in mouse oocytes. Results Generation and confirmation of mice lacking Aurka in oocytes Because AURKA can function in the CPC in the absence of AURKB and AURKC [31], we ...
Arabidopsis α- Aurora kinases (AUR1 and AUR2). Proteomics results revealed that TPX2- LIKE PROTEINS2 and 3 (TPXL2/3) prominently associated with α- Auroras , as did the conserved TPX2 to a lower degree. Like TPX2 ...
[6], [17]. In mitotically dividing cells, the CPC consists of a catalytic subunit, Aurora B kinase (AURKB), and regulatory subunits Inner Centromere Protein ( INCENP ), Survivin, and Borealin [18]–[20 ...
Abstract Aurora - like kinases play key roles in chromosome segregation and cytokinesis in yeast, plant, and animal systems. Here, we characterize three Arabidopsis thaliana protein kinases , designated ...
requires distinguishing between kinase -dependent and independent functions. In C. elegans, Aurora A and B (AIR-1 and AIR-2, respectively) are known to regulate essential events during both mitosis ...
Crossref Search ADS PubMed WorldCat 16 Tanaka TU , Rachidi N, Janke C et al. Evidence that the Ipl1-Sli15 ( Aurora kinase - INCENP ) complex promotes chromosome bi-orientation by altering kinetochore-spindle ...
. Aurora kinase is a serine/threonine kinase that plays essential roles in cell division (Carmena and Earnshaw 2003 ). In vertebrates, Aurora kinases are classified into three types, Aurora A, B and C ...
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