In vivo preclinical evaluation of the new 68Ga-labeled beta-cyclodextrin in prostaglandin E2 (PGE2) positive tumor model using positron emission tomography

In vivo preclinical evaluation of the new 68Ga-labeled beta-cyclodextrin in prostaglandin E2... International Journal of Pharmaceutics 576 (2020) 118954 Contents lists available at ScienceDirect International Journal of Pharmaceutics journal homepage: www.elsevier.com/locate/ijpharm In vivo preclinical evaluation of the new Ga-labeled beta-cyclodextrin in prostaglandin E2 (PGE2) positive tumor model using positron emission tomography a, a a a a b György Trencsényi , Adrienn Kis , Judit P. Szabó , Ágnes Ráti , Katalin Csige , Éva Fenyvesi , b b c a a d Lajos Szente , Milo Malanga , Gábor Méhes , Miklós Emri , István Kertész , Miklós Vecsernyés , d,1 a,1 Ferenc Fenyvesi , István Hajdu Division of Nuclear Medicine and Translational Imaging, Department of Medical Imaging, Faculty of Medicine, University of Debrecen, Nagyerdei St. 98, H-4032 Debrecen, Hungary Cyclolab Cyclodextrin R&D Laboratory Ltd., H-1097, Illatos St. 7, Budapest, Hungary Department of Pathology, Faculty of Medicine, University of Debrecen, Nagyerdei St. 98, H-4032 Debrecen, Hungary Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Nagyerdei St. 98, H-4032 Debrecen, Hungary ARTIC L E I NF O ABSTRAC T Keywords: The cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE2) pathway plays an important role in tumor development Ga and formation of metastases. It was earlier reported that cyclodextrin derivatives have a high affinity to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Pharmaceutics Elsevier

In vivo preclinical evaluation of the new 68Ga-labeled beta-cyclodextrin in prostaglandin E2 (PGE2) positive tumor model using positron emission tomography

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Publisher
Elsevier
Copyright
Copyright © 2020 Elsevier B.V.
ISSN
0378-5173
DOI
10.1016/j.ijpharm.2019.118954
Publisher site
See Article on Publisher Site

Abstract

International Journal of Pharmaceutics 576 (2020) 118954 Contents lists available at ScienceDirect International Journal of Pharmaceutics journal homepage: www.elsevier.com/locate/ijpharm In vivo preclinical evaluation of the new Ga-labeled beta-cyclodextrin in prostaglandin E2 (PGE2) positive tumor model using positron emission tomography a, a a a a b György Trencsényi , Adrienn Kis , Judit P. Szabó , Ágnes Ráti , Katalin Csige , Éva Fenyvesi , b b c a a d Lajos Szente , Milo Malanga , Gábor Méhes , Miklós Emri , István Kertész , Miklós Vecsernyés , d,1 a,1 Ferenc Fenyvesi , István Hajdu Division of Nuclear Medicine and Translational Imaging, Department of Medical Imaging, Faculty of Medicine, University of Debrecen, Nagyerdei St. 98, H-4032 Debrecen, Hungary Cyclolab Cyclodextrin R&D Laboratory Ltd., H-1097, Illatos St. 7, Budapest, Hungary Department of Pathology, Faculty of Medicine, University of Debrecen, Nagyerdei St. 98, H-4032 Debrecen, Hungary Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Nagyerdei St. 98, H-4032 Debrecen, Hungary ARTIC L E I NF O ABSTRAC T Keywords: The cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE2) pathway plays an important role in tumor development Ga and formation of metastases. It was earlier reported that cyclodextrin derivatives have a high affinity to

Journal

International Journal of PharmaceuticsElsevier

Published: Feb 25, 2020

References

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