The absorption of calcium by the human body is limited due to the formation of calcium phosphate deposits during gastrointestinal digestion. A new type of calcium delivery system was established using casein phosphopeptides (CPP) and soluble dietary fibers (SDF) through covalent binding. The physicochemical properties, morphology, calcium binding mechanisms, and in vitro calcium release behavior of the prepared CPP-SDF copolymers in a simulated gastrointestinal tract were investigated. The results showed that the maximum calcium binding level of the copolymers reached 46.8%, 35.17% (p < 0.05) greater than that of the original CPP. The calcium binding mechanism of the copolymers was the chemical grafting of active groups; exposed -CO-NH, -COOH and -OH groups and the imidazole group of His served as the major binding sites. In addition, the grafted SDF formed a shell to diminish the digestion of peptides and prolong the release of calcium in the gastrointestinal tract. Therefore, the prepared CPP-SDF copolymers are a promising calcium delivery vehicle for improving calcium bioavailability.
Food Hydrocolloids – Elsevier
Published: Jun 1, 2018
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