Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!
of diagnosis: detection, reporting and investigation of de novo variants in novel genes identified by clinical sequencing . Hum Mutat 2018 ; 39 : 1505 – 16 . Google Scholar Crossref Search ADS PubMed WorldCat 5 ...
. The availability of large amounts of biomedical data, characterized by large feature sets and sparse content, motivates the development of new methods to compute patient similarities able to fuse heterogeneous data ...
Abstract Biclustering is a technique of discovering local similarities within data. For many years the complexity of the methods and parallelization issues limited its application to big data ...
big data, electronic health records, precision medicine INTRODUCTION New health problems, medications, and regimens emerge on a daily basis. To understand their clinical impact in a timely manner, large ...
complicated the development of both personality tests and theory [17]. Faced with similar problems, the field of genetics has created atlases that allow researchers to easily identify a particular gene’s ...
biosimilars.20 As the biosimilars are “ highly ” similar and not identical to the reference products, it is not clear whether these subtle, “ clinically insignificant” but noted differences influence drug ...
and candidate gene) for new candidate gene identification projects. Another major difficulty involves proper annotation of functionally characterized genes. Many gene products are highly pleiotropic, shifting ...
when they cross the threshold of the conventional databases systems’ capacity in processing information [3]. Big data trends characterize various sectors including basic science [1, 4], business [5 ...
strain using mathematical models and “ big data” from clinical episode reporting systems in highly -connected, well-resourced populations such as the US military. The proportion pC of infections that become ...
in identifying target populations for these programs are drawn from extensive information on a large sample of patients; this information is usually referred to as big data. Concepts and terminology Definition ...
Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!