Available online at www.sciencedirect.com ScienceDirect Hydrogels for brain repair after stroke: an emerging treatment option 1 2 Lina Ratiba Nih , Stanley Thomas Carmichael and Tatiana Segura Stroke disability is the only major disease without an effective function is immediately impaired, the boundaries of the treatment. The substantial clinical burden of stroke in disabled core expand to the adjacent tissue over the course of days, survivors and the lack of a medical therapy that promotes spreading apoptotic death to a region that was initially recovery provide an opportunity to explore the use of distal from the occluded vessel and healthy at the stroke biomaterials to promote brain repair after stroke. Hydrogels can onset. Promoting tissue regeneration at the site of a wound be injected as a liquid and solidify in situ to form a gelatinous that is dynamic in space and time represents one of the solid with similar mechanical properties to the brain. These biggest challenges in regenerative medicine, as stroke biomaterials have been recently explored to generate pro- treatment is currently facing very limited therapeutic repair environments within the damaged organ. This review approaches and an extensive series of unsuccessful clinical highlights the clinical problem of stroke
Current Opinion in Biotechnology – Elsevier
Published: Aug 1, 2016
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