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components of the extracellular matrix at neutral pH. At present, 25 vertebrate MMPs and 22 human homologs have been identified. 1 These enzymes differ from other classes of proteinases by their dependence ...
Search ADS PubMed WorldCat 6 Dumin JA , Dickeson SK, Stricker TP, Bhattacharyya-Pakrasi M, Roby JD, Santoro SA, Parks WC. Pro-collagenase- 1 ( matrix metalloproteinase - 1 ) binds the alpha( 2 )beta( 1 ) integrin ...
for matrix metalloproteinases , Proteomics , 2006, vol. 6 (pg. 1192- 1199) Google Scholar CrossRef Search ADS PubMed 25 Park JH, Park SM, Park SH, Cho KH, Lee ST. Cleavage and functional loss of human ...
Crossref Search ADS PubMed WorldCat 25 Wehkamp J , Harder J, Wehkamp K et al. NF-kappaB- and AP- 1 -mediated induction of human beta defensin - 2 in intestinal epithelial cells by Escherichia coli Nissle 1917 ...
=pmcentrez&rendertype=abstract. Accessed June 2 , 2014. Google Scholar CrossRef Search ADS PubMed 2 . Schönbeck U, Mach F, Libby P. Generation of biologically active IL- 1 beta by matrix metalloproteinases ...
in inflammatory bowel disease. Gastroenterology. 1999; 117: 814– 822. CrossRef Search ADS PubMed 26 Stallmach A, Chan CC, Ecker KW, et al. Comparable expression of matrix metalloproteinases 1 and 2 in pouchitis ...
, and Antimicrobial Activity Defensins are antimicrobial peptides that contain 6 cysteine residues in a conserved spacing pattern (Fig. 1 ). Human and mouse defensins can be classified into 2 types that differ from each ...
: 522 – 5 . Google Scholar Crossref Search ADS PubMed WorldCat 26 Jang BC , Lim KJ, Suh MH, Park JG, Suh SI. Dexamethasone suppresses interleukin-1beta-induced human beta- defensin 2 mRNA expression ...
Search ADS PubMed 23. Niyonsaba F , Ushio H , Nagaoka I , Okumura K , Ogawa H . The human beta- defensins (- 1 , - 2 , -3, -4) and cathelicidin LL-37 induce IL-18 secretion through p38 and ERK MAPK activation ...
epithelial cells called Paneth cells, enteric α- defensins are broadly antimicrobial against bacterial and viral infections [ 1 –3]. In humans , the enteric α- defensin repertoire consists of human defensin 5 (HD5 ...
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