How Does Membrane Oxidation Affect Cell Delivery and Cell Killing?

How Does Membrane Oxidation Affect Cell Delivery and Cell Killing? The biophysical properties of cellular membranes intimately influence the delivery of cargoes into cells by cell-penetrating peptides (CPPs) and the bactericidal activity of antimicrobial peptides (AMPs). Here, we discuss how lipid oxidation creates important chemical and biophysical changes in membranes, and hypothesize about the observed synergy between oxidized membranes and membrane-active peptides. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Trends in Biotechnology Elsevier

How Does Membrane Oxidation Affect Cell Delivery and Cell Killing?

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Publisher
Elsevier Current Trends
Copyright
Copyright © 2017 Elsevier Ltd
ISSN
0167-7799
D.O.I.
10.1016/j.tibtech.2017.03.015
Publisher site
See Article on Publisher Site

Abstract

The biophysical properties of cellular membranes intimately influence the delivery of cargoes into cells by cell-penetrating peptides (CPPs) and the bactericidal activity of antimicrobial peptides (AMPs). Here, we discuss how lipid oxidation creates important chemical and biophysical changes in membranes, and hypothesize about the observed synergy between oxidized membranes and membrane-active peptides.

Journal

Trends in BiotechnologyElsevier

Published: Aug 1, 2017

References

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