Ghrelin acts centrally to induce an antinociceptive action during colonic distension through the orexinergic, dopaminergic and opioid systems in conscious rats

Ghrelin acts centrally to induce an antinociceptive action during colonic distension through the... •Intracisternal ghrelin induced an antinociception.•Peripheral ghrelin or central des-acyl-ghrelin does not induce antinociception.•Opioid, dopamine and orexinergic systems mediate the ghrelin’s action. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Brain Research Elsevier

Ghrelin acts centrally to induce an antinociceptive action during colonic distension through the orexinergic, dopaminergic and opioid systems in conscious rats

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Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier B.V.
ISSN
0006-8993
D.O.I.
10.1016/j.brainres.2018.02.024
Publisher site
See Article on Publisher Site

Abstract

•Intracisternal ghrelin induced an antinociception.•Peripheral ghrelin or central des-acyl-ghrelin does not induce antinociception.•Opioid, dopamine and orexinergic systems mediate the ghrelin’s action.

Journal

Brain ResearchElsevier

Published: May 1, 2018

References

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