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, and tion (ACEI) in congestive heart failure (CHF) is unknown. To prolongs survival in patients with CHF (2,3). The benefits clarify the level and functional effects of endogenous bradykinin of ACEI are due ...
ORIGINAL ARTICLE Vascular B1 Kinin Receptors in Patients With Congestive Heart Failure Ninian N. Lang, MRCP,* Nicholas L. Cruden, MRCP, PhD,* George H. Tse, MB, ChB,† Peter Bloomfield, MD, FRCP, FACC ...
, Little W. Functional effects of endogenous bradykinin in congestive heart failure. J Am Coll Cardiol . 1998 ; 31 : 1679 –1686 21 Torre-Amione G , Kapadia S, Benedict C, Oral K, Young J, Mann D ...
the production of prostacyclin by blocking cyclooxygenase. Prostaglandins play an important endogenous vasodilatory role and counteract the enhanced peripheral vasoconstriction state in congestive heart failure ...
dysfunction in patients with chronic heart failure.Eur Heart J.1998;19(suppl G):G48-G53.CPChengKOnishiNOhteMSuzukiWCLittleFunctional effects of endogenous bradykinin in congestive heart failure.J Am Coll ...
hypertrophy and restored renovascular endothelial function , but had only a modest effect on glomerular injury [6]. Vasopeptidase inhibitors and congestive heart failure In cardiomyopathic hamsters with CHF ...
for hypertension or congestive heart failure, and the promising effect seen after their combination, led to the development of drugs that simultaneously inhibit both enzyme systems. Neutral endopeptidase, like ACE ...
. Br J Pharmacol . 1994 ; 113 : 717 –722 [25] Barbe F , Su JB, Guyene TT, Crozatier B, Menard J, Hittinger L. Bradykinin pathway is involved in acute hemodynamic effects of enalaprilat in dogs with heart ...
provide a powerful combination in the treatment of hypertension or congestive heart failure by potentiating the effects of raised endogenous natriuretic peptides. That this might be the case was supported ...
. Enalapril was found to have beneficial effects in patients with left ventricular dysfunction, as well as to reduce long-term mortality in severe congestive heart failure (for reviews see [5,6]). Similar ...
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