FSH receptor binding inhibitor restrains follicular development and possibly attenuates carcinogenesis of ovarian cancer through down-regulating expression levels of FSHR and ERβ in normal ovarian tissues

FSH receptor binding inhibitor restrains follicular development and possibly attenuates... ObjectivesThe current study aimed to investigate FSH receptor binding inhibitor (FRBI) effects in the expressions of FSH receptor (FSHR) and estrogen receptor-beta (ERβ) in the mice ovaries at the gene and protein levels, also to find the potential efficacy of FRBI on suppressing ovarian cancer through down-regulating over-expression of FSHR and ERβ in the normal ovarian tissues. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Gene Elsevier

FSH receptor binding inhibitor restrains follicular development and possibly attenuates carcinogenesis of ovarian cancer through down-regulating expression levels of FSHR and ERβ in normal ovarian tissues

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Publisher
Elsevier
Copyright
Copyright © 2018 The Authors
ISSN
0378-1119
eISSN
1879-0038
D.O.I.
10.1016/j.gene.2018.05.068
Publisher site
See Article on Publisher Site

Abstract

ObjectivesThe current study aimed to investigate FSH receptor binding inhibitor (FRBI) effects in the expressions of FSH receptor (FSHR) and estrogen receptor-beta (ERβ) in the mice ovaries at the gene and protein levels, also to find the potential efficacy of FRBI on suppressing ovarian cancer through down-regulating over-expression of FSHR and ERβ in the normal ovarian tissues.

Journal

GeneElsevier

Published: Aug 20, 2018

References

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