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enzyme UBE2B. These data could cast light on how a component of the ubiquitin-proteasome pathway participates in the assembly of flagellar periaxonemal structures . Data in the literature support the notion ...
Flagellar dyskinesia is characterized by abnormal sperm movement parameters and a negative sperm mucus penetration test. It is associated with structural pathologies of the axonemal complex (lack ...
Although the generation of reactive oxygen species is an activity normally associated with phagocytic leucocytes, mammalian spermatozoa were, in fact, the first cell type in which this activity ...
., Lanzavecchia, S. et al. ( 1995) Flagellar structure in normal human spermatozoa and in spermatozoa that lack dynein arms. Tissue Cell. , 27, 241–247. Google Scholar Barros, A., Sausa, M., Angelopoulos, T ...
The sperm flagellum is a specialized type of motile cilium composed of a typical “9 + 2” axonemal structure with peri-axonemal structures , such as outer dense fibers (ODFs). This flagellar ...
Spermatozoa contain highly specialized structural features reflecting unique functions required for fertilization. Among them, the flagellum is a sperm-specific organelle required to generate ...
normal , indicating incomplete late spermiogenesis. Indeed, NGS confirmed gene deletions involved in flagellar development/function (AKAP4, SPAG16, CATSPER1). For the patient with proximal centriole defect ...
expression. The patients were both found to produce sperm that, although those showed no apparent defects in the flagellar structure , had reduced progressive motility. In contrast to mice, most sperm from ...
. Sperm motility ranged from normal to severe asthenozoospermia in the 10 patients (3–60% total motility values). Most spermatozoa showed small globular cephalic thickenings. These structures did ...
axonemal anomalies associated with normal fibrous sheaths (Chemes et al., 1998). One of the most severe abnormalities of sperm flagellar structure is the DFS. Although electron microscopy studies of semen ...
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