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). Far upstream element - binding protein 1 (FUBP1), also known as human DNA helicase V (HDH V), is a single-stranded DNA- binding protein encoded by the FUBP1 gene, and it regulates the expression of target ...
identified that far upstream element - binding protein 1 (FBP1), a transcriptional regulator of c -Myc that is one of the most frequently aberrantly expressed oncogenes in various human cancers, including NPC ...
therapeutic targets for its treatment . The human far upstream element (FUSE) binding protein 1 (FBP1) binds to the FUSE DNA sequence upstream of the c ‐Myc promoter and regulates its expression . FBP1 is also ...
:4115–4126 DOI 10.1007/s13277-015-4263-8 ORIGINAL ARTICLE Far upstream element - binding protein 1 (FUBP1) is a potential c -Myc regulator in esophageal squamous cell carcinoma (ESCC) and its expression ...
Abstract FUSE binding protein (FBP) binds in vivo and in vitro with the single-stranded far upstream element (FUSE) upstream of the c -myc gene. In addition to its transcriptional role, FBP and its ...
patients. Tumor Biol. (2016) 37:9755–9769 DOI 10.1007/s13277-016-4819-2 ORIGINAL ARTICLE The far - upstream element - binding protein 2 is correlated with proliferation and doxorubicin resistance in human breast ...
and relationship with FIRΔexon2, which is a splicing variant of the far - upstream element - binding protein (FUBP) 1 -interacting repressor (FIR) lacking exon 2, which fails to repress c -myc transcription in cancers ...
sequence significantly enhanced c -jun expression (2). Identification of a positive regulatory element in the upstream region of c -jun, spanning −148 to −124 region and its role in response to growth ...
Background. Far upstream element - binding protein 1 (FUBP1) is reported to be involved in cancer development by regulating the transcription of c -myc gene through binding to far upstream ...
, poly r( C ) binding protein 1 (PCBP1) and polypyrimidine tract binding protein (PTB), were found to increase the activity of the Bag‐ 1 IRES in vitro and in vivo . The regions of the Bag‐ 1 IRES RNA to which ...
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