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BackgroundGATA4 is an early cardiac-specific transcription factor, and endogenous GATA4-positive cells play a critical role in cardioprotection after myocardial injury. As functional paracrine units ...
] Exosomes : Nanoparticles Involved in Cardioprotection ? [Circ Res. 2014;114:325–332] Microvesicles as Cell–Cell Messengers in Cardiovascular Diseases Ali J. Marian, Editor Susmita Sahoo, Douglas W. Losordo ...
Mecp2 via miR-22.18 Giricz et al.19 reported that exosomes /microvesicles released from the rat heart after ischaemic preconditioning are critical for the cardioprotective effect of remote conditioning ...
, decreased caspase activation, and reduced cardiomyocyte apoptosis. PAPP-A knockdown prevented CPC exosome -mediated cardioprotection both in vitro and in vivo. Conclusion These results suggest that CPC ...
cardioprotection relative to BMMSCs or AdMSCs and supported enhanced microvessel density. Inhibitor studies indicated that the enhanced paracrine actions of EnMSCs were mediated by secreted exosomes . Analyses ...
in new tabDownload slide Ischaemia, Reperfusion, Cardioprotection , Haematopoietic cells, Exosomes This article is part of the Spotlight Issue on Cardioprotection Beyond the Cardiomyocyte. 1. Introduction ...
–Rem) despite timely and successful surgical mitral valve repair (MVR) remain unknown. Plasma exosomes (pEXOs) are smallest nanovesicles exerting early postoperative cardioprotection . We hypothesized ...
. Many of these constituents are biologically active. By exchanging bioactive molecules between cells, exosomes play central roles in cell-cell communication. An early analysis of exosomal mRNA identified ...
Background: Microvesicles (MVs) contain bioactive molecules critical to intracellular signaling and have cardioprotective effects in ischemia/reperfusion (IR) injury hearts. This study investigated ...
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