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promoter in the absence of exogenously provided ligand. This cell-based assay, henceforth named the 5BR assay, could be used to examine HCV polymerase activity in the absence of other HCV proteins. Mutations ...
. Dietary nucleotides may influence protein biosynthesis as well as signal membrane transduction mediated by the interaction of exogenous nucleosides and their receptors may also contribute to modulate ...
, but not βγ‐meATP, acted as a substrate for purified yeast NDPK to generate ATP via trans‐phosphorylation of ADP. αβ‐meATP also acted as substrate for the eNDPK activities expressed by 1321N1, PC12, and C6 ...
the expression of adenosine effects at low nucleoside concentrations usually requires guanine nucleotides, the effect of adding adenosine in the presence of 5 x 10–5 M Gpp(NH)p was examined. While either ...
-3 levels and HDAC activity while increasing the expressions of Ac-H3 and Ac-H4 proteins.Conclusions: We conclude that one mechanism by which uridine provides neuroprotection in neonatal rat HIE model ...
expression of CD54, CD80, CD83, CD86, HLA‐DR, and MHC class I molecules nor modulated secretion of interleukin (IL)‐12, IL‐10, and tumor necrosis factor alpha in immature and lipopolysaccharide‐matured DC ...
possess eRT activity . eRT activity was blocked with the non- nucleoside RT inhibitor nevirapine at concentrations within the therapeutic drug range. L1 elements are bicistronic, containing 2 open reading ...
of antigens and then to the activation of specific lymphocyte-effector mechanisms.42 Adenosine has been shown to modulate dendritic cell functions by interaction with specific receptors, the expression ...
Extracellular NAD is degraded to pyridine and purine metabolites by different types of surface‐located enzymes which are expressed differently on the plasmamembrane of various human cells and tissues ...
the exsCEBA promoter activity and ExoS production in ΔmiaB back to the wild-type level (Fig 4E and 4F). These results together suggested that MiaB modulated T3SS gene expression by recruiting the LadS. However ...
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