Ex vivo approach to studying bio-adhesive and tribological properties of artificial salivas for oral dryness (xerostomia)

Ex vivo approach to studying bio-adhesive and tribological properties of artificial salivas for... Saliva plays fundamental role in the maintenance of the good mouth health and in the lubrication process during oral functions including speech and mastication. Xerostomia, or dry mouth syndrome, is a disease due to an insufficient saliva secretion, or a total absence of saliva. The effects of xerostomia are very unpleasant in the daily life. They lead to some important inconveniences as the dental caries, the loss of teeth or some difficulties to speak.The causes of xerostomia are various but the most of the times they are often associated to irradiation and radiotherapy used to treat cancers of the head and neck. To try to re-wet the oral cavity, salivary substitutes are generally used. They are supposed to re-lubricate the mouth.In this work, a method for measuring adhesion and lubrication of the salivary substitutes has been tested ex vivo on pig tongue. The results indicated that the bio-adhesive properties of the salivary substitutes were fairly close to those of human saliva, while their lubricate capacity were rather less efficient. The experimental method proposed here seems to be interesting to characterise and improve the salivary substitutes performances. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Wear Elsevier

Ex vivo approach to studying bio-adhesive and tribological properties of artificial salivas for oral dryness (xerostomia)

Loading next page...
 
/lp/elsevier/ex-vivo-approach-to-studying-bio-adhesive-and-tribological-properties-O7hWXfxCcp
Publisher
Elsevier
Copyright
Copyright © 2015 Elsevier B.V.
ISSN
0043-1648
eISSN
1873-2577
D.O.I.
10.1016/j.wear.2015.02.020
Publisher site
See Article on Publisher Site

Abstract

Saliva plays fundamental role in the maintenance of the good mouth health and in the lubrication process during oral functions including speech and mastication. Xerostomia, or dry mouth syndrome, is a disease due to an insufficient saliva secretion, or a total absence of saliva. The effects of xerostomia are very unpleasant in the daily life. They lead to some important inconveniences as the dental caries, the loss of teeth or some difficulties to speak.The causes of xerostomia are various but the most of the times they are often associated to irradiation and radiotherapy used to treat cancers of the head and neck. To try to re-wet the oral cavity, salivary substitutes are generally used. They are supposed to re-lubricate the mouth.In this work, a method for measuring adhesion and lubrication of the salivary substitutes has been tested ex vivo on pig tongue. The results indicated that the bio-adhesive properties of the salivary substitutes were fairly close to those of human saliva, while their lubricate capacity were rather less efficient. The experimental method proposed here seems to be interesting to characterise and improve the salivary substitutes performances.

Journal

WearElsevier

Published: May 1, 2015

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off