•Optimal ensemble framework for HIV-1 protease cleavage site prediction.•Optimal formation of encoding-classifier pair selection by evolutionary algorithm.•Natural selection in number of base learners and optimal data-learner mapping.•Credibility of propsed enesmble model in cross-domain prediction.•Experiment on benchmark data and statistical comparison with current state of art.
Expert Systems with Applications – Elsevier
Published: Nov 1, 2018
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