•This is the 39th annual review of research concerning the endogenous opioid system.•It reviews 2016 papers about opioid peptides and receptors and their analgesic roles.•It reviews 2016 papers about opioid roles in stress, tolerance, dependence and abuse.•It reviews 2016 papers about opioid roles in learning, ingestion, hormones and mood.•It reviews 2016 papers about opioid roles in activity, immune and other bodily function.
Peptides – Elsevier
Published: Mar 1, 2018
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