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and participants in the CLARITY study, we have witnessed how the application of science to protect public health has been hindered. That environmentally relevant exposures to BPA (and other endocrine disruptors ...
observed in the field and, in some cases, provide mechanisms to explain the effects. About 10 years ago the discussion of “ endocrine disrupters” broadened from a focus on environmental estrogens to include ...
introduction of endocrine disruptors into the environment, inspired Wingspread participants as well as other scientists to ignore the commonsensical, but mistaken, assurance that weak hormones at low doses were ...
spurred a flurry of research on mechanisms of toxicity, new questions about how to deal with cumulative exposures to endocrine -active compounds (EACs) from man-made, dietary, and endogenous sources ...
origin of fertility and metabolic disorders. Studies with the environmental endocrine disruptor bisphenol A (BPA) show that reproductive disruptions found in prenatal BPA-treated sheep are similar to those ...
) was predicted by Dr. Colborn to explain abnormalities being observed in wildlife due to exposure to environmental chemicals that disrupted endocrine function. This prediction led to the 1991 Wingspread conference ...
, Sonnenschein C 2002 Endocrine disruptors : from Wingspread to environmental developmental biology. J Steroid Biochem Mol Biol 83 : 235 – 244 Google Scholar Crossref Search ADS PubMed WorldCat 17 Kuiper GG ...
environmental exposure (7). BPA is an estrogen agonist that can bind to both classical nuclear estrogen receptors (ERs), ERα and ERβ (33, 34). In addition, data from recent studies have revealed that low levels ...
Humans are routinely exposed to bisphenol-A (BPA), an estrogenic compound that leaches from dental materials, food and beverage containers, and other plastic consumer products. Effects of perinatal ...
) Google Scholar Crossref Search ADS PubMed WorldCat Soto AM , Sonnenschein C . Environmental causes of cancer: endocrine disruptors as carcinogens , Nat. Rev. Endocrinol. , 2010 , vol. 6 (pg. 363 - 370 ...
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