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NO production and the nitric oxide synthase (NOS) activity in CC. The concentration of cyclic guanosine monophosphate ( cGMP ) and cyclic adenosine monophosphate ( cAMP ) in CC were also examined by enzyme-linked ...
effective than RFEB in increasing corticosterone-suppressed ACTH levels, enhancing CRH levels and cAMP / cGMP ratio, and reducing oxidative damage. In vivo, PFEB significantly increased eNOS and inhibited PDE5 ...
Abstract Endothelial production of nitric oxide (nitrogen monoxide, NO) has become a major research area in vascular biology. Some of the most important effects that NO exerts in the vascular wall ...
The positive contractile effect of nitric oxide (NO) donors was studied on isolated rat ventricular cardiomyocytes within a range of a positive force/frequency relationship. We determined whether ...
monophosphate ( cGMP ) signaling pathway is the most important inducer of erectile tissue relaxation [2]. NO is produced by endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) from ...
, including the oxidation of sGC, NO˙ dissociation from sGC, and cGMP degradation by PDE, had a profound effect on enhancing cGMP accumulation as compared with other reaction steps. Using combined perturbations ...
this same level of organization is preserved in the connections the photoreceptors make in the central nervous system of the animal. The work presented here investigates the role of the nitric oxide signaling ...
resolved. In particular, specific roles for cyclic (c)GMP in mammalian sperm are poorly understood. In this study, we have characterized comparatively the cAMP and cGMP signalling systems in ejaculated human ...
involve inositol phosphate and cAMP . In as much as nitric oxide (NO) and its mediator cGMP have been recently shown to contribute substantially to the response of somatotrophs to key regulatory hormones ...
, cAMP , and cGMP were reduced, compared to control. Losartan alone reduced MAP, and increased renal GSH, plasma nitric oxide , angiotensin II, aldosterone, and aortic cGMP . When administered concurrently ...
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