1 Introduction</h5> Secondary caries refers to carious lesions affecting the margins of existing restorations. 1,2 It has been widely demonstrated to be the most common reason for replacement of failed restorations in permanent and primary teeth, regardless of the type of restorative material. 3–7 Secondary caries showed similar initiation and arrestment processes to primary caries, 1 resulting from acids and enzymes produced by dental biofilms. 8 Composites are popular tooth cavity filling materials, 9–14 and composite restorations are bonded to the tooth structure using adhesives. 15–22 Therefore, efforts have been made to develop antibacterial composites and adhesives that could kill bacteria and reduce or avoid the formation of biofilms. 23–27 Antibacterial quaternary ammonium methacrylates (QAMs) were synthesized and incorporated into dental resins. 28–33 In addition, antibacterial adhesives were proposed to be beneficial when the clinical situation prevented complete caries removal. 34 </P>In pioneering work on the development of antibacterial restoratives containing QAMs, 12-methacryloyloxydodecylpyridinium bromide (MDPB) was incorporated into composites, 24 primer and adhesive. 23–35 Methacryloxylethyl cetyl dimethyl ammonium chloride (DMAE-CB) was also developed and served as a component for antibacterial bonding agents. 25,36 Another study developed the poly(quaternary ammonium salt)-containing polyacid to formulate the light-curable glass-ionomer cements. 26
Journal of Dentistry – Elsevier
Published: Jun 1, 2013
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