Effect of nutrient deprivation on the expression and the epigenetic signature of sirtuin genes

Effect of nutrient deprivation on the expression and the epigenetic signature of sirtuin genes Background and aimOver the last decades advances in understanding the molecular bases of the close relationship between nutrition, metabolism, and diseases have been impressive. However, there are always novel frontiers coming up and epigenetics is one of these. Sirtuins, are pivotal factors in the control of metabolic pathways according to nutrient availability. In the present study we evaluated the effect of nutrient deprivation on expression, DNA methylation and chromatin status of the sirtuin genes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nutrition, Metabolism and Cardiovascular Diseases Elsevier

Effect of nutrient deprivation on the expression and the epigenetic signature of sirtuin genes

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Publisher
Elsevier
Copyright
Copyright © 2018 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University
ISSN
0939-4753
D.O.I.
10.1016/j.numecd.2018.02.004
Publisher site
See Article on Publisher Site

Abstract

Background and aimOver the last decades advances in understanding the molecular bases of the close relationship between nutrition, metabolism, and diseases have been impressive. However, there are always novel frontiers coming up and epigenetics is one of these. Sirtuins, are pivotal factors in the control of metabolic pathways according to nutrient availability. In the present study we evaluated the effect of nutrient deprivation on expression, DNA methylation and chromatin status of the sirtuin genes.

Journal

Nutrition, Metabolism and Cardiovascular DiseasesElsevier

Published: Apr 1, 2018

References

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