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predicted that the compound can potentially bind strongly to the Cyclin E1-Cdk2 complex which is a key mediator of the cell cycle progression indicating a biological interference in aggressive prostate cancer ...
and -negative human prostate cancer lines LNCaP and JCA-1, respectively. Inhibition of cell growth by 50% (ED50) in LNCaP cells was seen at concentrations of 60.8 ± 3.2 and 29.8 ± 2.2 µm baicalin and baicalein ...
of these three flavonoids against human PCA cells . Carcinogenesis vol.26 no.4 pp.845--854, 2005 doi:10.1093/carcin/bgi014 Acacetin inhibits cell growth and cell cycle progression , and induces apoptosis in human ...
Effects of Dietary Flavonoid —‘Ashwagandha’ in Prostate Cancer Cells 1 2 1 1 Ravikumar Aalinkeel , Zihua Hu , Bindukumar B. Nair , Donald E. Sykes , 1 1 1 Jessica L. Reynolds , Supriya D. Mahajan and Stanley ...
mechanism is still unclear. In this study, we tested the inhibitory effects of wogonoside in human prostate cancer PC3 cells in vitro and vivo. Methods: The effects of wogonoside on cell viability, cycle ...
Apigenin, a common dietary flavonoid abundantly present in fruits and vegetables, may have the potential for prevention and therapy for prostate cancer . Here, we report for the first time ...
mechanisms that feature in preclinical studies including motivation of carcinogen detoxification, scavenging of free radical species, control of cell cycle progression , preventing the initiation of cancer ...
), the major prenylated flavonoid of hops, has been shown to have chemopreventive properties relevant to the suppression of cancer development in the initiation, promotion and progression phases (Gerhäuser ...
The discovery and cloning of the cyclin-dependent kinases (cdks), main regulators of cell cycle progression , allowed several investigators to design novel modulators of cdk activity. Flavopiridol ...
., ). The mechanisms underlying BA‐presented anticancer effects include arrest of cancer cell cycle progress , ...
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