Current Opinion in Genetics & Development 2014, 27 :v–vii</P>For a complete overview see the Issue </P>Available online 2nd July 2014</P>http://dx.doi.org/10.1016/j.gde.2014.06.007 </P>0959-437X/© 2014 Elsevier Ltd. All right reserved.</P>Innovations ‘sense’ order in developmental mechanisms and evolution</h5> The recent surge in technological advances, including novel imaging tools, higher resolution microscopy and high-throughput sequencing has greatly improved our understanding of developmental biology, genetics and evolutionary processes. These new tools have facilitated many paradigm-shifting discoveries and enhanced our knowledge of basic biological systems. The reviews comprised in this issue of Current Opinion in Genetics and Development illustrate exciting innovations in many aspects of transcriptional regulation and cell biology that impact developmental mechanisms, patterning and evolution. Each review demonstrates how these new approaches are allowing us to confirm or revise existing models and raise exciting new biological questions.</P>Cellular compartmentalization brings order to developmental signaling</h5> Strategies to gain efficiency within the intracellular milieu (signaling) and the nucleus (transcription) are highlighted in this issue, as well as how changes in these systems may be selected for evolutionary adaptation. One of the fundamental concepts in developmental biology is that of a morphogen: a signal that is produced in one cell and which acts on neighboring cells to
Current Opinion in Genetics & Development – Elsevier
Published: Aug 1, 2014
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