DNA transfer: Review and implications for casework

DNA transfer: Review and implications for casework 1 Introduction to ‘trace DNA’</h5> With the increasing sensitivities of both the standard and LT-DNA techniques, DNA that cannot be attributed to a particular biological source, such as blood, saliva, etc., can now be profiled. Several different terms have been coined to describe such DNA. For example, the term ‘touch DNA’ has been used, but this can be misleading in two ways: Firstly, such a term infers that the DNA recovered from a surface got there via that surface being touched, but this is usually not known, and secondly, there is a misconception that ‘touch DNA’ can only be detected by LT-DNA techniques.</P>The term ‘trace DNA’ is now gaining more usage over ‘touch DNA’, but can have various meanings; it could refer to the amount of DNA present, the quality of DNA present, or to DNA detected by a LT-DNA technique [1] . In this review the term ‘trace DNA’ refers solely to DNA that cannot yet be attributed to an identifiable body fluid. The inability to identify a body fluid source, combined with the difficulties described in this paper, have given an impetus to research to improve the sensitivity and specificity of the identification of body fluids http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Forensic Science International: Genetics Elsevier

DNA transfer: Review and implications for casework

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Publisher
Elsevier
Copyright
Copyright © 2013 Elsevier Ireland Ltd
ISSN
1872-4973
eISSN
1878-0326
D.O.I.
10.1016/j.fsigen.2013.03.013
Publisher site
See Article on Publisher Site

Abstract

1 Introduction to ‘trace DNA’</h5> With the increasing sensitivities of both the standard and LT-DNA techniques, DNA that cannot be attributed to a particular biological source, such as blood, saliva, etc., can now be profiled. Several different terms have been coined to describe such DNA. For example, the term ‘touch DNA’ has been used, but this can be misleading in two ways: Firstly, such a term infers that the DNA recovered from a surface got there via that surface being touched, but this is usually not known, and secondly, there is a misconception that ‘touch DNA’ can only be detected by LT-DNA techniques.</P>The term ‘trace DNA’ is now gaining more usage over ‘touch DNA’, but can have various meanings; it could refer to the amount of DNA present, the quality of DNA present, or to DNA detected by a LT-DNA technique [1] . In this review the term ‘trace DNA’ refers solely to DNA that cannot yet be attributed to an identifiable body fluid. The inability to identify a body fluid source, combined with the difficulties described in this paper, have given an impetus to research to improve the sensitivity and specificity of the identification of body fluids

Journal

Forensic Science International: GeneticsElsevier

Published: Jul 1, 2013

References

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