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for Toxicogenomic Studies A highly stable transcription profile was obtained for all treatments (FDR≤0.0005) as in our previous microarray study in the 3T3-L1 cell line (Pereira-Fernandes et al., 2013b). However ...
to enhance the LLNA and support further exploration of this approach through examination of a more diverse array of chemicals. LLNA, sensitization, microarray Determination of the contact sensitization ...
. However, early applications of microarray technology have identified relatively small groups of responding genes with which to define new targets for analysis by conventional means. We have trialled a more ...
. Google Scholar Crossref Search ADS PubMed WorldCat 5. Lettieri T . Recent applications of DNA microarray technology to toxicology and ecotoxicology . Environ Health Perspect . 2006 ; 114 ( 1 ): 4 – 9 ...
in response to disease. The greatest advances to date in the application of “omics” technologies to EDC biomarker development have been in the field of toxicogenomics . Both commercial and custom DNA microarray ...
, such as springtails, supplement traditional ecotoxicological research but are presently rather descriptive. Classifier analysis, a more analytical application of the microarray technique, is able to predict biological ...
describe the use of a complementary DNA (cDNA) microarray of the fathead minnow (Pimephales promelas) a standard sentinel organism in aquatic toxicology, to better understand the mechanisms of toxicity ...
: Applications for toxicogenomics in risk assessment Toxicol. Sci. 2008 105 233 234 Google Scholar CrossRef Search ADS PubMed Daston GP Naciff JM Gene expression changes related to growth and differentiation ...
identification of chemicals. The aim of this study was to use gene expression profiling to identify the toxicities and potentially relevant human diseases due to endosulfan exposure. We performed DNA microarray ...
on the search for genetic biomarkers that could be used in environmental pollution assessments in freshwater ecosystems. Chironomus, ecotoxicology , transcriptome, gene expression, metabolic pathways Introduction ...
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