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-methoxylated indolic GS 4MI3G and subsequent hydrolysis by the atypical myrosinase PEN2 (Clay et al., 2009). This discovery revealed an important regulatory function of breakdown products of indolic GSs ...
of aliphatic acids of different chain lengths esterified to sucrose, or less frequently to glucose. Through liquid chromatography-mass spectrometry screening of introgression lines, we previously identified ...
proteins to attempted invasion sites (Kwon et al., 2008; Wang et al., 2009). Also, chemical responses involving the Trp-derived phytoalexin camalexin and indolic glucosinolates protect cells against ...
on their chemical structure. These include short chain fatty acids, hydroxamic acid derivatives, benzamides, cyclic peptides, and a few substrates not assignable to these categories. The most commonly used HDACis ...
-hydroxypyrrole-2-carboxylic acid at the starter position. JBIR-34 is a 4-methyloxazoline- containing NRP with 6-chloro-4-hydroxy- indole -3-carboxylic acid, d-Ala, and l-Ser amino acid units [78]. The A-CP didomain ...
basis underlying the biosynthesis of β-diketones remains unclear. Here, we discovered that the wheat W1 locus contains a metabolic gene cluster mediating β-diketone biosynthesis. The cluster comprises ...
pharmaceutical companies forming large research programs centered on natural products discovery . These programs aimed to identify new secondary metabolites with a variety of novel biological activities, including ...
. antibiotic resistance breakers, ESKAPEE, efflux pump inhibitors, membrane permeabilisers, beta-lactamase inhibitors, combination therapy INTRODUCTION Since their discovery more than 70 years ago, antibacterial ...
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