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to amphotericin B , 7-oxo- amphotericin B had a lower antifungal activity but an approximately 10-fold decrease in hemolytic activity . Surprisingly, neither antifungal activity nor hemolytic activity was detected ...
to validate the efficacy of selective serotonin reuptake inhibitors, fluoxetine hydrochloride (FLH) and paroxetine hydrochloride (PAH), alone and in combination with amphotericin B (AmB) against C. neoformans ...
antifungals , itraconazole and amphotericin B were conducted as above and the 2-fold serially diluted test concentrations ranged from 0.25 to 125 μg/ml. Time-kill kinetics assay For time-kill kinetics of WSWE ...
to reduce the toxicity of antifungals . In this study, we evaluated the combination of N-acetylcysteine (NAC) with amphotericin B (AMB) for the treatment of cryptococcosis. We examined the effects of NAC ...
(1,3)-β-D-glucan, resulting in loss of cell integrity [5]. The third most commonly employed antifungal is the polyene drug amphotericin B (AmB), which was the standard of care for ∼40 years [6]. Its ...
, these treatments have not yet been evaluated in formal clinical trials. Combining multiple antifungals has also proven effective against many pathogens. Amphotericin B is used as a conventional treatment for several ...
against biofilm are rare, liposomal amphotericin B is credited with an antibiofilm activity in some opportunistic species of the genus Candida. Using freshly isolated strains from hospital environment ...
. Google Scholar CrossRef Search ADS PubMed [7] Brajtburg J. Bolard J. ( 1996) Carrier effects on biological activity of amphotericin B . Clin. Microbiol. Rev. 9, 512– 531. Google Scholar PubMed [8 ...
–51 Similarly, lipid formulations of amphotericin B (liposomal and lipid complex) were shown to also possess potent antifungal activity , in preclinical studies as well as case reports.48,52–55 Owing ...
and was treated over time with various antifun- with CMC due to AIRE mutations were tested against VT-1598 and fluconazole (FLC), gals ( amphotericin B , micafungin, terbinafine, voriconazole, posaconazole), adjunct ...
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